The main character is a Filipina Overseas Contract Worker, one of the many residents of the archipelago who is forced to leave her family and take a higher paying job in a more prosperous ...

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She was one of the top 10 Questors or Magic Circle of 10, and after few weeks of training, made it to the final 5 or Magic Circle of 5.

In the Grand Questor's Night, she was declared as the 4th runner up.

After the contest, she guested in some TV shows of ABS-CBN particularly in the youth oriented drama SCQ Reload and variety show ASAP Fanatic.

Melissa received one of her biggest breaks when she portrayed Hiyas, the apple of Pedro Penduko's eyes in the Fantaserye Komiks Presents: Da Adventures of Pedro Penduko and when she starred in the primetime drama series Iisa Pa Lamang led by Claudine Barreto.

, the Philippine adaptation of the Chilean 2009 drama ¿Dónde está Elisa? She then played her biggest break in the role of Johanna Montenegro in the multi-acclaimed phenomenal primetime drama series, Walang Hanggan.

She currently appears as Leah Layer in Honesto, where she reunites with her Walang Hanggan co-stars' Paulo Avelino and Noni Buencamino.

This 2015 She is the lead actress of the upcoming kick off film of The Light Cinema entitled "Ligaw" as Criselle.

She starred in Kambal sa Uma, an afternoon drama series on ABS-CBN with Shaina Magdayao, Rio Locsin, Matt Evans and Jason Abalos.

She came back abruptly to Primetime on the hit series Tanging Yaman in 2010 alongside Erich Gonzales.

Melissa is currently a member of ABS CBN's Star Magic.

During the 2011-2012 season, she portrayed Elisa Altamira in Nasaan Ka Elisa?